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Cholecystitis

What is it?

Cholecycstitis is a painful inflammation of the gallbladder, the small, pear-shaped sac under the liver that stores bile. Bile is a liquid in the liver that helps to digest food in the intestine.

Who gets it?

Cholecystitis strikes twice as many women than men, particularly those between the ages of twenty and sixty. Pregnant women, or those on birth control pills or estrogen replacement therapy have a greater risk of developing cholecystitis. People who are overweight, or who lose a large amount of weight quickly are also at greater risk for developing the condition.

What causes it?

In about ninety-five percent of all cases of cholecystitis, the gallbladder contains gallstones. Gallstones are solid accumulations of the components of bile, which occur when the components of bile are not in correct proportion to each other. A gallstone blocking the outlet from the gallbladder usually causes acute cholecystitis, so that bile cannot get out. The bile can become concentrated and infected, causing the condition.

Chronic (reoccurring) cholecystitis occurs when the gallbladder walls have become permanently damaged by repeated attacks of acute cholecystitis.

Rare causes of cholecystitis include severe burns or injury, massive systemic infection, severe illness, diabetes, obstruction by a tumor of the duct leaving the gallbladder, and certain uncommon infections of the gallbladder (including bacteria and worms).

What are the symptoms?

Symptoms of cholecystitis include constant pain in the right upper abdomen. It is usually made worse by moving. The patient may have a fever and sometimes jaundiced skin. Other symptoms include indigestions and nausea. Eating fatty foods will often make the symptoms worse. When the bacterial infection sets in, many patients experience a higher fever and shaking chills.

How is it diagnosed?

Cholecystitis can be difficult for a doctor to diagnose because its symptoms resemble those of other illnesses. If a doctor suspects cholecystitis after a physical exam of the patient, the doctor may perform an abdominal ultrasound to create an image of the internal organs and measure the thickness of the gallbladder wall (a maker of inflammation and scarring). Other imaging tests may also be performed to see the liver, bile ducts, gallbladder and upper part of the small intestine. In addition, a blood test will reveal an increase in the white blood count, as well as an increase in bilirubuin.

What is the treatment?

To treat cholecystitis, the doctor will usually hospitalize the patient and remove the gallbladder, either immediately after diagnosis or after the patient has improved. Occasionally, patients with complications require surgery immediately after diagnosis. Patients who have cholecystitis with no gallstones have about a fifty percent chance of death if the gallbladder is not quickly removed. Called a cholecystectomy, the procedure can be performed using a laparoscope (a tube inserted through small incisions) or by conventional surgery.

If the patient has other serious medical problems that may increase the risks of gallbladder removal surgery, the surgeon may decide to leave the gallbladder in place.  In this case, an operation called a cholecystotomy may be performed to remove obstructing gallstones and drain infected bile.

Self-care tips

To help prevent cholecystitis, the patient should maintain an ideal weight and follow a diet high in fiber, vegetables and fruit.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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