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Erectile Dysfunction

Also known as: Impotence

What is it?

Erectile dysfunction, or impotence, is the inability to achieve or maintain an erection long enough for the penis to enter the vagina and engage in sexual intercourse.

Who gets it?

Erectile dysfunction affects approximately 10-20 million American men and it strikes up to half of all men between the ages of 40 and 70. Midlife and the later years bring changes in circulation that may affect the sex organs.

What causes it?

In older men, physical causes play a primary role in 60% or more of all cases of erectile dysfunction. In men over the age of 60, the leading cause is atherosclerosis, or narrowing of the arteries, which can restrict the flow of blood to the penis. Injury or disease of the connective tissue, such as Peyronie's disease, may also interfere. Damage to the nerves of the penis from certain types of surgery or neurological conditions such as Parkinson's disease or multiple sclerosis may also cause erectile dysfunction. Men with diabetes are especially at risk for impotence because of their high risk of both atherosclerosis and a nerve disease called diabetic neuropathy. Other causes include the use of certain drugs, including certain types of blood pressure medications, antihistamines, tranquilizers (especially before intercourse), and antidepressants. Smoking, excessive alcohol consumption, and illicit drug use may also contribute. In rare cases, low levels of the male hormone testosterone can cause erectile failure. Finally, psychological factors, such as stress, guilt, or anxiety, may also play a role, even when the impotence is primarily due to organic causes.

What are the symptoms?

The primary symptom of erectile dysfunction is the inability of the penis to achieve or maintain an erection long enough to engage in sexual intercourse. Erectile dysfunction is diagnosed when the symptoms last longer than two months or are reoccurring.

How is it diagnosed?

To diagnose erectile dysfunction, a doctor may begin by asking a number of questions to determine the underlying cause. A look at a patient’s medical history to find out about past pelvic surgery, diabetes, cardiovascular disease, kidney disease, and any medications the man may be taking may also reveal a cause. The physical examination may include a genital examination, a measurement of blood flow through the penis, hormone tests, and a glucose test for diabetes. In some cases, nocturnal penile tumescence testing is performed to find out whether the patient has erections while asleep.

What is the treatment?

Various treatments for erectile dysfunction exist depending on the cause. Vacuum therapy may be used in which the patient inserts his penis into a clear plastic cylinder and uses a pump to force air out of the cylinder to form partial vacuum around the penis, which helps to draw blood into the corpora cavernosa. Injection therapy involves injecting a substance into the penis to enhance blood flow and cause an erection. In a long-awaited breakthrough, a pill for combating impotence was cleared for marketing by the FDA in March 1998. Called sildenafil citrate (brand name Viagra), the drug boosts levels of a substance called cyclic GMP, which is responsible for widening the blood vessels of the penis. Viagra has been shown to be effective in about 70-80% of men who take it, and it can even work in men with some psychological component to their impotence. Unlike drugs that are injected into the penis, Viagra causes an erection only when the man is sexually aroused. Implantable penile prostheses are usually considered a last resort for treating impotence. They are implanted in the corpora cavernosa to make the penis rigid without the need for blood flow. A number of herbs have been promoted for treating erectile dysfunction, including Coryanthe yohimbe (available by prescription as yohimbine) and gingko (Gingko biloba), although neither has been conclusively shown to help the condition in controlled studies.

Self-care tips

While there are no specific treatments to prevent erectile dysfunction, maintaining general good health by exercising regularly, controlling weight, controlling hypertension and high cholesterol levels, and avoiding smoking and alcohol can help.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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