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Trigeminal Neuralgia

Also known as:  Tic Douloureux, which is French for painful twitch

What is it?

Trigeminal neuralgia is a disorder of the trigeminal nerve, the 5th cranial nerve that carries sensations of touch, pain, pressure, and temperature from the face to the brain.  People with trigeminal neuralgia experience episodes of sharp, piercing pain that can affect the cheek, lips, gums, or chin on one side of the face.

Who gets it?

Trigeminal neuralgia usually occurs after the age of 70 and is unusual in anyone under the age of 50.  It affects women three times more frequently than men.  This condition may also occur in younger people with multiple sclerosis.

What causes it?

Doctors are not exactly sure what causes this disorder, but believe it could be the degeneration or irritation of the trigeminal nerve.  Some believe the pain occurs when an abnormally formed artery puts pressure on the nerve.  The trigeminal nerve is divided into three branches and is responsible for chewing, producing saliva and tears, and sending facial sensations to the brain.   Doctors can tell which branch is affected by the location of the pain. Neuralgia of the first branch causes pain around the eyes and over the forehead. Neuralgia of the second branch causes pain in the upper lip, nose, and cheek.  Neuralgia of the third branch causes pain on the side of the tongue and lower lip.

What are the symptoms?

Trigeminal neuralgia is characterized by pain that occurs suddenly and spontaneously.  People describe this excruciating pain as feeling like an electric shock.  The pain is usually so severe that it prevents the person from doing anything else during an attack.  Pain usually begins from the same area of the face each time, often in the cheek next to the nose or in the jaw area. Pain is more severe at the ends of the affected nerve, especially over the nostrils, lip, chin, or teeth.  Often, the pain is triggered by touching a certain spot on the face, such as when washing or shaving, or even by activities such as eating, drinking, or talking.  At first, the episodes of pain are brief and it could be weeks before another attack.  They could come and go for days, weeks, or months at a time, and then disappear altogether for months or even years.  With time, however, the episodes occur more frequently and become even more painful.  In some people, the pain occurs as much as 100 times a day.  In these cases, trigeminal neuralgia can cause people to limit their activities because they are so fearful of another attack.

How is it diagnosed?

There is no specific test for trigeminal neuralgia, but its symptoms are so specific that it is easy to diagnose.  Your doctor will first evaluate other possible causes of facial pain, such as problems with the jaw, teeth, or sinuses.  He or she will also check whether a tumor or aneurysm is putting pressure on the trigeminal nerve.

What is the treatment?

Typical pain medications may not be effective with trigeminal neuralgia because the pain is brief and does not occur at regular, predictable intervals.  Antiseizure drugs, such as carbamazepine and phenytoin, are often used to suppress pain because they slow down the nerve signals at certain nerve terminals. Because these types of drugs can cause a number of different side effects, your doctor will monitor your dosage carefully and may need to try different types of drugs to control the discomfort.  The symptoms usually return, however, when medication is stopped.  In cases where drug treatment is not effective, the nerve can be deadened with gamma rays, radio frequency waves, or glycerol injections.  The nerve can also be cut or permanently destroyed.  This type of treatment, however, can leave lasting facial discomfort and is only used in severe cases.  If trigeminal neuralgia is caused by an artery or tumor compressing the nerve, surgery may be needed to free the nerve from the source of pressure and permanently relieve the pain. Your doctor should make sure you are aware of all the risks and possible complications associated with any surgical treatment.

Self-care tips

Although there is no way to prevent trigeminal neuralgia, you can take steps to avoid attacks if you know what triggers them.  For example, avoid very cold or very hot food and drinks, don't chew your food on the side that is painful, donŐt eat extremely hard or crunchy foods, avoid splashing your face with very hot or cold water when washing, and rinse your mouth with water after every meal instead of using a toothbrush.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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