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Vulvar Cancer

See also:  Reproductive Cancer

What is it?

Vulvar cancer is a rare disease that occurs mainly in elderly women. Women with this cancer are more likely to recover if the cancer is diagnosed and treated early.

Vulvar Cancer refers to an abnormal, cancerous growth in the external female genitalia.

Who gets it and what are its causes?

Vulvar cancer is a rare disease that occurs mainly in older women. The vulva refers to the external female genitalia, which includes the labia, the opening of the vagina, the clitoris, and the space between the vagina and anus (perineum). Vulvar cancer can affect any part of the female genitalia, but usually affects the labia. Most vulvar cancers are squamous cell carcinomas. Squamous cells are the main cell type of the skin. Squamous cell carcinoma often begins at the edges of the labia majora or labia minora or the area around the vagina. This type of cancer is usually slow growing and may begin with a precancerous condition referred to as vulvar intraepithelial neoplasti, or dysplasia. This means that precancerous cells are present in the surface layer of skin.

Other less common types of vulvar cancer are melanoma, basal cell carcinoma, adenocarcinomas, Paget’s disease of the vulva and tumors of the connective tissue under the skin. Melanoma, a cancer that develops from the cells that produce the pigment that determines the skin’s color, can occur anywhere on the skin, including the vulva. It’s the second most common type of vulvar cancer, and account for about 4% of cases. Basal cell carcinoma, which is the most common type of cancer that occurs on parts of the skin exposed to the sun, very rarely occurs on the vulva. Adenocarcinomas develop from glands, including the glands at the opening of the vagina that produce a mucus-like lubricating fluid.

Vulvar cancer is most common in women over 50 years of age. Additional risk factors for vulvar cancer include having multiple sexual partners, cervical cancer, and the presence of chronic vaginal and vulvar inflammations. This type of cancer is often associated with sexually transmitted diseases.

What are the symptoms?

Vulvar Cancer-If squamous cell vulvar cancer is present, it may appear as a raised red, pink or white nodule. Itching, pain, bleeding, vaginal discharge and painful urination often accompany it. Malignant melanoma of the vulva usually appears as a pigmented, ulcerated growth. Other types of vulvar cancer may appear as a distinct mass of tissue, sore and scaly areas, or cauliflower-like growths that look like warts. Any abnormalities should be reported to a gynecologist for examination.

Medical Treatment

The risk of cancer of the vulva can be decreased by reducing the risk factors for the cancer, most of which involve lifestyle factors. Specifically, to reduce the risk of vulvar cancer, women should not smoke and should refrain from engaging in risky sexual behavior. Good hygiene of the genital area to prevent infection and inflammation may also reduce the risk of vulvar cancer.

Regular examinations are necessary to detect precancerous conditions that can be treated before the cancer becomes invasive. Since some vulvar cancer is a type of skin cancer, the American Cancer Society also recommends self-examination of the vulva using a mirror.

Surgical Treatment

Treatment for this cancer will depend on its stage and the patient’s general state of health. The primary treatment is surgery to remove the affected area and possibly the associated lymph nodes. The surgery may be done by laser, to burn off a minimal amount of tissue, or scalpel to remove more of the tissue. The choice will depend on the severity of the cancer.

If a large area of the vulva is removed, it is called a vulvectomy. A vulvectomy may require skin grafts from other areas of the body to cover the wound. Surgery may also be followed by chemotherapy and radiation therapy to kill additional cancer cells. All three of these procedures have risks associated with them, which should be discussed with the caregiver.

Physician's Who Treat Ovarian Cancer


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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